Provides flexible framework for agent-based simulation of outbreaks among in-patients in a generic-but-realistic network of short/long-stay hospitals and nursing homes, as well as interventions to mitigate transmission and inter-facility spread. Scenarios(s) Modeled: Initial invasion of new pathogen / strain and/or endemic pathogens. Intervention scenarios for patient-targeted efforts including surveillance and isolation (contact precautions), vaccination, and anti-microbial drug treatment.
Additional Resource Information:
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1-Slayton R, Toth D, Lee B, Tanner W, Bartsch S, Khader K, Wong K, Brown K, McKinnell J, Ray W, Miller L, Rubin M, Kim D, Adler F, Cao C, Avery L, Stone N, Kallen A, Samore M, Huang S, Fridkin S, Jernigan J (2015). Vital Signs: estimated effects of a coordinated approach for action to reduce antibiotic-resistant infections in health care facilities – United States. MMWR Morb Mortal Wkly Rep, 64(30), 826-831. https://doi.org/10.1111/ajt.13555. 2-Toth D, Khader K, Slayton R, Kallen A, Gundlapalli A, O’Hagan J, Fiore A, Rubin M, Jernigan J, Samore M (2017). The potential for interventions in a long-term acute care hospital to reduce transmission of carbapenem-resistant Enterobacteriaceae in affiliated healthcare facilities. Clin Infect Dis, 65(4), 581-587. https://doi.org/10.1093/cid/cix370., 3-Toth D, Keegan L, Samore M, Khader K, O’Hagan J, Yu H, Quintana A, Swerdlow D (2020). Modeling the potential impact of administering vaccines against Clostridioides difficile infection to individuals in healthcare facilities. Vaccine, 38(37), 5927-5932. https://doi.org/10.1016/j.vaccine.2020.06.081.
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- Epidemic Model – Scenario Modeling
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